Preoperative Right Ventricular Dysfunction Indicates High Vasoactive Support Needed After Cardiac Surgery

Pei Chi Ting, Victor C.C. Wu, Chia Chih Liao, An Hsun Chou, Feng Chun Tsai, Pyng Jing Lin, Chun Yu Chen, Shao Wei Chen*

*此作品的通信作者

研究成果: 期刊稿件文章同行評審

20 引文 斯高帕斯(Scopus)

摘要

Objective: The aim of this study was to explore the relationship between preoperative right ventricular (RV) function and high vasoactive-inotropic score (VIS) after cardiac surgery. Design: Prospective observational study. Setting: A single medical center setting. Participants: One hundred three patients undergoing elective cardiac surgery. Interventions: None. Measurements and Main Results: Consecutive patients referred for cardiac surgery were enrolled prospectively. Comprehensive transesophageal echocardiography was performed before sternal incision. Specific RV indices, encompassing RV fractional area change, tricuspid annular plane systolic excursion, and RV global longitudinal strain (RVGLS), were measured offline. High VIS was defined as a maximum VIS of ≥20 in 24 hours postoperatively. Postoperative adverse events were recorded. One hundred three patients (mean age 61.2 ± 11.0, 72 men) were included in this study, where 17 patients (16.5%) achieved high VIS with a mean maximum VIS of 39 in 24 hours postoperatively. Patients with high VIS encountered increased occurrence of extracorporeal membrane oxygenation placement, acute kidney injury, and mortality. Risk factors for high VIS included operation type, cardiopulmonary bypass duration, left atrium size, and pre-incisional RV indices. After adjustment for age, left ventricular ejection fraction, and the covariates, only RVGLS (odds ratio 1.19, p = 0.011) showed an independent association with high VIS. The optimal cutoff of RVGLS was −16.7% (sensitivity of 88.2%, specificity of 75.6%). Conclusion: Preoperative RV dysfunction is an independent risk factor for postoperative high VIS. Pre-incisional RVGLS is a reliable tool to predict high VIS after cardiac surgery. Patients with high VIS had increased adverse events postoperatively.

原文英語
頁(從 - 到)686-693
頁數8
期刊Journal of Cardiothoracic and Vascular Anesthesia
33
發行號3
DOIs
出版狀態已出版 - 03 2019
對外發佈

文獻附註

Publisher Copyright:
© 2018 Elsevier Inc.

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