Recent progresses in gene delivery-based bone tissue engineering

Chia Hsin Lu, Yu Han Chang, Shih Yeh Lin, Kuei Chang Li, Yu Chen Hu*

*此作品的通信作者

研究成果: 期刊稿件文獻綜述同行評審

104 引文 斯高帕斯(Scopus)

摘要

Gene therapy has converged with bone engineering over the past decade, by which a variety of therapeutic genes have been delivered to stimulate bone repair. These genes can be administered via in vivo or ex vivo approach using either viral or nonviral vectors. This article reviews the fundamental aspects and recent progresses in the gene therapy-based bone engineering, with emphasis on the new genes, viral vectors and gene delivery approaches.

原文英語
頁(從 - 到)1695-1706
頁數12
期刊Biotechnology Advances
31
發行號8
DOIs
出版狀態已出版 - 12 2013

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