Responses of midbrain dorsal raphe neurons to ethanol studied in brainstem slices

Nai Shin Chu; Larry Keenan

doi:10.1016/0741-8329(87)90069-3

Responses of midbrain dorsal raphe neurons to ethanol studied in brainstem slices

Nai Shin Chu^*, Larry Keenan

^*此作品的通信作者

University of California at Irvine

研究成果: 期刊稿件 › 文章 › 同行評審

18 引文斯高帕斯（Scopus）

摘要

The effects of ethanol on midbrain dorsal raphe (DR) neurons were studied using the brainstem slice preparations. Ethanol in low doses (100 mg% and 200 mg%) exerted more excitation than inhibition on DR cells. Higher doses of ethanol produced inhibition in the majority of DR neurons. The present data indicate that the effects of ethanol were biphasic with low concentrations tending to excite and high concentrations to inhibit DR neurons.

原文	英語
頁（從 - 到）	373-374
頁數	2
期刊	Alcohol
卷	4
發行號	5
DOIs	https://doi.org/10.1016/0741-8329(87)90069-3
出版狀態	已出版 - 1987
對外發佈	是

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abstract = "The effects of ethanol on midbrain dorsal raphe (DR) neurons were studied using the brainstem slice preparations. Ethanol in low doses (100 mg% and 200 mg%) exerted more excitation than inhibition on DR cells. Higher doses of ethanol produced inhibition in the majority of DR neurons. The present data indicate that the effects of ethanol were biphasic with low concentrations tending to excite and high concentrations to inhibit DR neurons.",

keywords = "Brain slice, Dorsal raphe neurons, Ethanol",

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AB - The effects of ethanol on midbrain dorsal raphe (DR) neurons were studied using the brainstem slice preparations. Ethanol in low doses (100 mg% and 200 mg%) exerted more excitation than inhibition on DR cells. Higher doses of ethanol produced inhibition in the majority of DR neurons. The present data indicate that the effects of ethanol were biphasic with low concentrations tending to excite and high concentrations to inhibit DR neurons.

KW - Brain slice

KW - Dorsal raphe neurons

KW - Ethanol

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U2 - 10.1016/0741-8329(87)90069-3

DO - 10.1016/0741-8329(87)90069-3

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AN - SCOPUS:0023407002

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VL - 4

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JF - Alcohol

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Responses of midbrain dorsal raphe neurons to ethanol studied in brainstem slices

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