Retinoic acid induction of mouse cellular retinoic acid-binding protein-I gene expression is enhanced by sphinganine

Li Na Wei; Chih Hao Lee; Liming Chang

doi:10.1016/0303-7207(95)03570-W

Retinoic acid induction of mouse cellular retinoic acid-binding protein-I gene expression is enhanced by sphinganine

Li Na Wei^*
, Chih Hao Lee
, Liming Chang

^*此作品的通信作者

University of Minnesota Twin Cities

研究成果: 期刊稿件 › 文章 › 同行評審

22 引文斯高帕斯（Scopus）

摘要

Cellular retinoic acid-binding protein-I (CRABP-I) gene expression is induced in mouse embryonal carcinoma P19 cells specifically by retinoic acid (RA) and the induction is enhanced by sphinganine. The effects of retinoic acid and sphinganine on CRABP-I gene expression can be accounted for by a stimulation of its transcription rate. Using a lacZ reporter system, it was determined that a DNA fragment containing a putative AP-1 binding site in the promoter region of CRABP-I gene is required for the up-regulation of CRABP-I gene transcription.

原文	英語
頁（從 - 到）	207-211
頁數	5
期刊	Molecular and Cellular Endocrinology
卷	111
發行號	2
DOIs	https://doi.org/10.1016/0303-7207(95)03570-W
出版狀態	已出版 - 06 1995
對外發佈	是

UN SDG

此研究成果有助於以下永續發展目標

SDG3 健康與福祉

存取文件

10.1016/0303-7207(95)03570-W

其它文件與鏈接

Link to publication in Scopus

引用此

@article{e907b65e49af406ba4a9edc17c383945,

title = "Retinoic acid induction of mouse cellular retinoic acid-binding protein-I gene expression is enhanced by sphinganine",

abstract = "Cellular retinoic acid-binding protein-I (CRABP-I) gene expression is induced in mouse embryonal carcinoma P19 cells specifically by retinoic acid (RA) and the induction is enhanced by sphinganine. The effects of retinoic acid and sphinganine on CRABP-I gene expression can be accounted for by a stimulation of its transcription rate. Using a lacZ reporter system, it was determined that a DNA fragment containing a putative AP-1 binding site in the promoter region of CRABP-I gene is required for the up-regulation of CRABP-I gene transcription.",

keywords = "AP-1, Cellular retinoic acid-binding protein-I, Gene regulation, Sphinganine",

author = "Wei, \{Li Na\} and Lee, \{Chih Hao\} and Liming Chang",

year = "1995",

month = jun,

doi = "10.1016/0303-7207(95)03570-W",

language = "英语",

volume = "111",

pages = "207--211",

journal = "Molecular and Cellular Endocrinology",

issn = "0303-7207",

publisher = "Elsevier Ireland Ltd",

number = "2",

}

TY - JOUR

T1 - Retinoic acid induction of mouse cellular retinoic acid-binding protein-I gene expression is enhanced by sphinganine

AU - Wei, Li Na

AU - Lee, Chih Hao

AU - Chang, Liming

PY - 1995/6

Y1 - 1995/6

N2 - Cellular retinoic acid-binding protein-I (CRABP-I) gene expression is induced in mouse embryonal carcinoma P19 cells specifically by retinoic acid (RA) and the induction is enhanced by sphinganine. The effects of retinoic acid and sphinganine on CRABP-I gene expression can be accounted for by a stimulation of its transcription rate. Using a lacZ reporter system, it was determined that a DNA fragment containing a putative AP-1 binding site in the promoter region of CRABP-I gene is required for the up-regulation of CRABP-I gene transcription.

AB - Cellular retinoic acid-binding protein-I (CRABP-I) gene expression is induced in mouse embryonal carcinoma P19 cells specifically by retinoic acid (RA) and the induction is enhanced by sphinganine. The effects of retinoic acid and sphinganine on CRABP-I gene expression can be accounted for by a stimulation of its transcription rate. Using a lacZ reporter system, it was determined that a DNA fragment containing a putative AP-1 binding site in the promoter region of CRABP-I gene is required for the up-regulation of CRABP-I gene transcription.

KW - AP-1

KW - Cellular retinoic acid-binding protein-I

KW - Gene regulation

KW - Sphinganine

UR - https://www.scopus.com/pages/publications/0029002113

U2 - 10.1016/0303-7207(95)03570-W

DO - 10.1016/0303-7207(95)03570-W

M3 - 文章

C2 - 7556883

AN - SCOPUS:0029002113

SN - 0303-7207

VL - 111

SP - 207

EP - 211

JO - Molecular and Cellular Endocrinology

JF - Molecular and Cellular Endocrinology

IS - 2

ER -

Retinoic acid induction of mouse cellular retinoic acid-binding protein-I gene expression is enhanced by sphinganine

摘要

UN SDG

存取文件

其它文件與鏈接

指紋

引用此