Retinopathy of prematurity and maternal age

Wei Chi Wu*, Frank Shih Chang Ong, Jane Zea Chin Kuo, Chi Chun Lai, Ning Chia Wang, Kuan Jen Chen, Yih Shiou Hwang, Tun Lu Chen, Chia Pang Shih

*此作品的通信作者

研究成果: 期刊稿件文章同行評審

31 引文 斯高帕斯(Scopus)

摘要

Purpose: To determine the risk factors, especially maternal risk factors, associated with the development of retinopathy of prematurity (ROP) in premature babies. Methods: A matched case-control study involving premature patients was undertaken retrospectively. The case group consisted of premature babies with the subsequent development of ROP. The control group consisted of gestational age-matched and sex-matched premature babies that did not develop ROP during the follow-up period. Risk factors involving patient demographics and maternal characteristics were compared between the case and control groups. Results: A total of 144 patients were included in this study (72 patients in the case group and 72 patients in the control group). Among the 66 possible risk factors compared, only birth weight and maternal age were found to be significant risk factors. Birth weight was significantly lower in the case group (1,248.7 ± 257.8 g vs. 1,335.5 ± 297.2 g, P = 0.01), and maternal age was significantly older in the case group compared with that in the control group (31.2 ± 5.1 years vs. 28.2 ± 5.3 years, P < 0.001). The odds ratio of having babies with ROP was 2.9 when the maternal age was >30 years. Conclusion: Older maternal age is a newly identified risk factor for the development of ROP in premature babies.

原文英語
頁(從 - 到)327-331
頁數5
期刊Retina
30
發行號2
DOIs
出版狀態已出版 - 02 2010

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