Shortened pain response time following repeated algesiometric tests in rats

Yuan Yang Lai; Samuel H.H. Chan

doi:10.1016/0031-9384(82)90184-6

Shortened pain response time following repeated algesiometric tests in rats

Yuan Yang Lai
, Samuel H.H. Chan^*

^*此作品的通信作者

Indiana State University

研究成果: 期刊稿件 › 文章 › 同行評審

32 引文斯高帕斯（Scopus）

摘要

Administration of the hot-plate test once every week for 5 to 8 weeks resulted in a progressive shortening of pain response time in spontaneously hypertensive, normotensive Wistar-Kyoto and Charles River rats. Furthermore, this gradual change in nociceptive response did not appear to be affected by the strain, degree of maturity, or blood pressure status of the animals. It is speculated that re-exposure of the rats to the same algesiometric test may result in "learning," habituation or anticipatory escape behavior.

原文	英語
頁（從 - 到）	1111-1113
頁數	3
期刊	Physiology and Behavior
卷	28
發行號	6
DOIs	https://doi.org/10.1016/0031-9384(82)90184-6
出版狀態	已出版 - 06 1982
對外發佈	是

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abstract = "Administration of the hot-plate test once every week for 5 to 8 weeks resulted in a progressive shortening of pain response time in spontaneously hypertensive, normotensive Wistar-Kyoto and Charles River rats. Furthermore, this gradual change in nociceptive response did not appear to be affected by the strain, degree of maturity, or blood pressure status of the animals. It is speculated that re-exposure of the rats to the same algesiometric test may result in {"}learning,{"} habituation or anticipatory escape behavior.",

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AB - Administration of the hot-plate test once every week for 5 to 8 weeks resulted in a progressive shortening of pain response time in spontaneously hypertensive, normotensive Wistar-Kyoto and Charles River rats. Furthermore, this gradual change in nociceptive response did not appear to be affected by the strain, degree of maturity, or blood pressure status of the animals. It is speculated that re-exposure of the rats to the same algesiometric test may result in "learning," habituation or anticipatory escape behavior.

KW - Hyperalgesia

KW - Repeated hot-plate test

UR - https://www.scopus.com/pages/publications/0020319930

U2 - 10.1016/0031-9384(82)90184-6

DO - 10.1016/0031-9384(82)90184-6

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Shortened pain response time following repeated algesiometric tests in rats

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