Synthesis of stereodefined z-vinyl iodides from carbohydrates as a prelude to C/D ring assembly in taxanes

Leo A. Paquette*, Tzenge Lien Shih, Qingbei Zeng, John E. Hofferberth

*此作品的通信作者

研究成果: 期刊稿件文章同行評審

6 引文 斯高帕斯(Scopus)

摘要

D-Mannitol has been transformed into 10 and 14, while D-glucose has served as precursor to 20. In the latter example, key steps include stereocontrolled vinylation, oxidative fragmentation of the tetrahydrofuran- 2,3-diol, oxetane ring closure, and highly stereoselective iodoolefination.

原文英語
頁(從 - 到)3519-3522
頁數4
期刊Tetrahedron Letters
40
發行號18
DOIs
出版狀態已出版 - 30 04 1999
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