The in vitro and in vivo anticancer properties of chalcone flavokawain B through induction of rosmediated apoptotic and autophagic cell death in human melanoma cells

Biochemistry, Genetics and Molecular Biology

• Apoptosis 100%
• Cell Death 100%
• Autophagy 100%
• Anticancer 100%
• Nude Mouse 60%
• Growth 40%
• Cell Viability 40%
• Caspase 3 40%
• Protein 20%
• Kinase 20%
• Serine 20%
• Proto Oncogene 20%
• Western Blot 20%
• Flow Cytometry 20%
• Mammalian Target of Rapamycin 20%
• Acetylcysteine 20%
• Annexin 20%
• In Vivo Study 20%
• Light Chain 20%
• Threonine 20%
• B Cell 20%
• Poly ADP Ribose Polymerase 20%
• Mortality Rate 20%
• MTT Assay 20%
• Fluorescence Microscopy 20%
• Sequestosome 1 20%
• Microtubule-Associated Protein 20%
• Bromide 20%
• Extracellular Signal-Regulated Kinases 20%
• Protein Kinase B 20%
• B-1 Cell 20%

Medicine and Dentistry

• In Vitro 100%
• Programmed Cell Death 100%
• Chalcone 100%
• Melanoma Cell 100%
• Autophagy 62%
• Nodular Melanoma 50%
• Reactive Oxygen Species 37%
• Cells 25%
• Cell Viability 25%
• Caspase 3 25%
• B-Cell Lymphoma 25%
• Melanoma Cell Line 25%
• Therapeutic Procedure 12%
• Protein 12%
• Skin 12%
• Mortality Rate 12%
• Protein Kinase B 12%
• Mechanistic Target of Rapamycin 12%
• Mitogen-Activated Protein Kinase 12%
• Antioxidant 12%
• MTT Assay 12%
• Growth 12%
• Flow Cytometry 12%
• Tumor Progression 12%
• Neoplasm 12%
• Skin Cancer 12%
• Fluorescence Microscopy 12%
• Lipocortin 5 12%
• Protein Serine Threonine Kinase 12%
• Beclin 1 12%
• B Raf Kinase 12%
• Sequestosome 1 12%
• Proto Oncogene 12%
• Lymph Node 12%
• Poly ADP Ribose Polymerase 12%
• Microtubule Associated Protein 12%
• Light Chain 12%
• Acetylcysteine 12%
• 3 Methyladenine 12%
• Chloroquine 12%
• 3 (4,5 Dimethyl 2 Thiazolyl) 2,5 Diphenyltetrazolium Bromide 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Melanoma 100%
• Chalcone 100%
• Cell Death 100%
• Apoptosis 50%
• Nude Mouse 30%
• Caspase 3 20%
• B Cell Lymphoma 20%
• Cell Viability 20%
• Protein 10%
• Antioxidant 10%
• Acetylcysteine 10%
• Flow Cytometry 10%
• Neoplasm 10%
• Mortality Rate 10%
• Mammalian Target of Rapamycin 10%
• Protein Kinase B 10%
• Mitogen Activated Protein Kinase 10%
• Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase 10%
• Tumor Growth 10%
• Lipocortin 5 10%
• Skin Cancer 10%
• 3 (4,5 Dimethyl 2 Thiazolyl) 2,5 Diphenyltetrazolium Bromide 10%
• Beclin 1 10%
• B Raf Kinase 10%
• Protein Serine Threonine Kinase 10%
• Microtubule Associated Protein 10%
• Chloroquine 10%
• 3 Methyladenine 10%
• Sequestosome 1 10%