Thermoplastic polyurethane/polylactic acid tissue scaffold fabricated by twin screw extrusion and microcellular injection molding

Hao Yang Mi, Xin Jing, Brianna Jacques, Lih Sheng Turng*, Xiang Fang Peng

*此作品的通信作者

研究成果: 圖書/報告稿件的類型會議稿件同行評審

摘要

Polylactic acid (PLA) and thermoplastic polyurethane (TPU) are two kinds of biocompatible and biodegradable polymers that can be used in biomedical applications. They possess rigid and flexible mechanical properties. The TPU/PLA blend tissue scaffolds at different ratios were fabricated via twin screw extrusion and micro-cellular injection molding techniques (a. k. a. MuCell) for the first time. Multiple test methods were used in this study. Fourier transform infrared spectroscopy (FTIR) verified the presence of the two components in the blends. Differential scanning calorimetry (DSC) and dynamic mechanical analysis (DMA) confirmed the immiscibility between TPU and PLA. Scanning electron microscopy (SEM) images affirmed that the PLA was dispersed as spheres or islands inside the TPU matrix, and that the phase morphology further influenced the surface roughness of cells. The blends exhibited a wide range of mechanical properties that cover most human tissue requirements. It was found from DMA and viscosity tests that 25% PLA significantly reinforces the blends at low temperatures or deformation frequencies.

原文英語
主出版物標題71st Annual Technical Conference of the Society of Plastics Engineers 2013, ANTEC 2013
發行者Society of Plastics Engineers
頁面1610-1614
頁數5
ISBN(列印)9781632665300
出版狀態已出版 - 2013
對外發佈
事件71st Annual Technical Conference of the Society of Plastics Engineers 2013, ANTEC 2013 - Cincinnati, OH, 美國
持續時間: 22 04 201324 04 2013

出版系列

名字Annual Technical Conference - ANTEC, Conference Proceedings
2

Conference

Conference71st Annual Technical Conference of the Society of Plastics Engineers 2013, ANTEC 2013
國家/地區美國
城市Cincinnati, OH
期間22/04/1324/04/13

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