Transcriptome Analysis of Common Gene Expression in Human Mesenchymal Stem Cells Derived from Four Different Origins

Tzu Hao Wang; Yun Shien Lee; Shiaw Min Hwang

doi:10.1007/978-1-60761-999-4_29

Transcriptome Analysis of Common Gene Expression in Human Mesenchymal Stem Cells Derived from Four Different Origins

Tzu Hao Wang, Yun Shien Lee, Shiaw Min Hwang^*

^*此作品的通信作者

臨床醫學研究所(含碩博士班)

Food Industry Research and Development Institute

研究成果: 圖書/報告稿件的類型 › 章節 › 同行評審

13 引文斯高帕斯（Scopus）

摘要

We have used Affymetrix oligonucleotide microarrays to analyze common transcriptomes and thereby learn about the core gene expression profile in human mesenchymal stem cells (MSC) from different tissues, including fetal amniotic fluid-derived MSC, term pregnancy amniotic membrane-derived MSC, term pregnancy umbilical cord blood-derived MSC, and adult bone marrow-derived MSC. The beauty of microarray analysis of gene expression (MAGE) is that it can be used to discover associating genes that were previously thought to be unrelated to a physiological or pathological event. However, interpreting complex biological processes from gene expression profiles often requires extensive knowledge mining in biomedical literature. In this chapter, we describe, step-by-step, how to use a commercially available biological database and software program, MetaCore (GeneGo Inc.), for functional network analysis.

原文	英語
主出版物標題	Methods in Molecular Biology
發行者	Humana Press Inc.
頁面	405-417
頁數	13
DOIs	https://doi.org/10.1007/978-1-60761-999-4_29
出版狀態	已出版 - 2011

出版系列

名字	Methods in Molecular Biology
卷	698
ISSN（列印）	1064-3745
ISSN（電子）	1940-6029

文獻附註

Publisher Copyright:
© 2011, Springer Science+Business Media, LLC.

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10.1007/978-1-60761-999-4_29

其它文件與鏈接

Link to publication in Scopus

引用此

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abstract = "We have used Affymetrix oligonucleotide microarrays to analyze common transcriptomes and thereby learn about the core gene expression profile in human mesenchymal stem cells (MSC) from different tissues, including fetal amniotic fluid-derived MSC, term pregnancy amniotic membrane-derived MSC, term pregnancy umbilical cord blood-derived MSC, and adult bone marrow-derived MSC. The beauty of microarray analysis of gene expression (MAGE) is that it can be used to discover associating genes that were previously thought to be unrelated to a physiological or pathological event. However, interpreting complex biological processes from gene expression profiles often requires extensive knowledge mining in biomedical literature. In this chapter, we describe, step-by-step, how to use a commercially available biological database and software program, MetaCore (GeneGo Inc.), for functional network analysis.",

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KW - Bone marrow

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Transcriptome Analysis of Common Gene Expression in Human Mesenchymal Stem Cells Derived from Four Different Origins

摘要

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