Transcriptome Analysis of Common Gene Expression in Human Mesenchymal Stem Cells Derived from Four Different Origins

Tzu Hao Wang, Yun Shien Lee, Shiaw Min Hwang*

*此作品的通信作者

研究成果: 圖書/報告稿件的類型章節同行評審

13 引文 斯高帕斯(Scopus)

摘要

We have used Affymetrix oligonucleotide microarrays to analyze common transcriptomes and thereby learn about the core gene expression profile in human mesenchymal stem cells (MSC) from different tissues, including fetal amniotic fluid-derived MSC, term pregnancy amniotic membrane-derived MSC, term pregnancy umbilical cord blood-derived MSC, and adult bone marrow-derived MSC. The beauty of microarray analysis of gene expression (MAGE) is that it can be used to discover associating genes that were previously thought to be unrelated to a physiological or pathological event. However, interpreting complex biological processes from gene expression profiles often requires extensive knowledge mining in biomedical literature. In this chapter, we describe, step-by-step, how to use a commercially available biological database and software program, MetaCore (GeneGo Inc.), for functional network analysis.

原文英語
主出版物標題Methods in Molecular Biology
發行者Humana Press Inc.
頁面405-417
頁數13
DOIs
出版狀態已出版 - 2011

出版系列

名字Methods in Molecular Biology
698
ISSN(列印)1064-3745
ISSN(電子)1940-6029

文獻附註

Publisher Copyright:
© 2011, Springer Science+Business Media, LLC.

指紋

深入研究「Transcriptome Analysis of Common Gene Expression in Human Mesenchymal Stem Cells Derived from Four Different Origins」主題。共同形成了獨特的指紋。

引用此