Treatment with High-dose Methylprednisolone for Hepatic Veno-occlusive Disease in a Child with Rhabdomyosarcoma

I. Lun Chen; San Nan Yang; Chih Cheng Hsiao; Kuan Sheng Wu; Jiunn Ming Sheen

doi:10.1016/S1875-9572(08)60029-7

Treatment with High-dose Methylprednisolone for Hepatic Veno-occlusive Disease in a Child with Rhabdomyosarcoma

I. Lun Chen
, San Nan Yang
, Chih Cheng Hsiao
, Kuan Sheng Wu
, Jiunn Ming Sheen^*

^*此作品的通信作者

Kaohsiung Medical University
Chang Gung University

研究成果: 期刊稿件 › 文章 › 同行評審

11 引文斯高帕斯（Scopus）

摘要

Hepatic veno-occlusive disease (VOD), also called sinusoidal obstruction syndrome, is rapidly progressing and involves life-threatening complications that can occur in patients receiving chemotherapy and/or bone marrow transplantation. No completely satisfactory treatment strategies have yet been established. We present a case of rhabdomyosarcoma in a 21-month-old boy who developed pancytopenia, dyspnea, jaundice, massive ascites and body weight gain of more than 10% after receiving conventional chemotherapy. Hepatic VOD was diagnosed. He recovered after supportive care and treatment with high-dose methylprednisolone.

原文	英語
頁（從 - 到）	141-144
頁數	4
期刊	Pediatrics and Neonatology
卷	49
發行號	4
DOIs	https://doi.org/10.1016/S1875-9572(08)60029-7
出版狀態	已出版 - 08 2008

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10.1016/S1875-9572(08)60029-7

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title = "Treatment with High-dose Methylprednisolone for Hepatic Veno-occlusive Disease in a Child with Rhabdomyosarcoma",

abstract = "Hepatic veno-occlusive disease (VOD), also called sinusoidal obstruction syndrome, is rapidly progressing and involves life-threatening complications that can occur in patients receiving chemotherapy and/or bone marrow transplantation. No completely satisfactory treatment strategies have yet been established. We present a case of rhabdomyosarcoma in a 21-month-old boy who developed pancytopenia, dyspnea, jaundice, massive ascites and body weight gain of more than 10\% after receiving conventional chemotherapy. Hepatic VOD was diagnosed. He recovered after supportive care and treatment with high-dose methylprednisolone.",

keywords = "chemotherapy, child, methylprednisolone, rhabdomyosarcoma, veno-occlusive disease",

author = "Chen, \{I. Lun\} and Yang, \{San Nan\} and Hsiao, \{Chih Cheng\} and Wu, \{Kuan Sheng\} and Sheen, \{Jiunn Ming\}",

year = "2008",

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doi = "10.1016/S1875-9572(08)60029-7",

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T1 - Treatment with High-dose Methylprednisolone for Hepatic Veno-occlusive Disease in a Child with Rhabdomyosarcoma

AU - Chen, I. Lun

AU - Yang, San Nan

AU - Hsiao, Chih Cheng

AU - Wu, Kuan Sheng

AU - Sheen, Jiunn Ming

PY - 2008/8

Y1 - 2008/8

N2 - Hepatic veno-occlusive disease (VOD), also called sinusoidal obstruction syndrome, is rapidly progressing and involves life-threatening complications that can occur in patients receiving chemotherapy and/or bone marrow transplantation. No completely satisfactory treatment strategies have yet been established. We present a case of rhabdomyosarcoma in a 21-month-old boy who developed pancytopenia, dyspnea, jaundice, massive ascites and body weight gain of more than 10% after receiving conventional chemotherapy. Hepatic VOD was diagnosed. He recovered after supportive care and treatment with high-dose methylprednisolone.

AB - Hepatic veno-occlusive disease (VOD), also called sinusoidal obstruction syndrome, is rapidly progressing and involves life-threatening complications that can occur in patients receiving chemotherapy and/or bone marrow transplantation. No completely satisfactory treatment strategies have yet been established. We present a case of rhabdomyosarcoma in a 21-month-old boy who developed pancytopenia, dyspnea, jaundice, massive ascites and body weight gain of more than 10% after receiving conventional chemotherapy. Hepatic VOD was diagnosed. He recovered after supportive care and treatment with high-dose methylprednisolone.

KW - chemotherapy

KW - child

KW - methylprednisolone

KW - rhabdomyosarcoma

KW - veno-occlusive disease

UR - https://www.scopus.com/pages/publications/56849122409

U2 - 10.1016/S1875-9572(08)60029-7

DO - 10.1016/S1875-9572(08)60029-7

M3 - 文章

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AN - SCOPUS:56849122409

SN - 1875-9572

VL - 49

SP - 141

EP - 144

JO - Pediatrics and Neonatology

JF - Pediatrics and Neonatology

IS - 4

ER -

Treatment with High-dose Methylprednisolone for Hepatic Veno-occlusive Disease in a Child with Rhabdomyosarcoma

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