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Ultra high phase sensitive surface plasmon resonance biosensor

  • Ying Chang Li
  • , Chien Chou*
  • *此作品的通信作者
  • National Central University
  • National Yang Ming Chiao Tung University

研究成果: 圖書/報告稿件的類型會議稿件同行評審

摘要

This study demonstrates a novel phase-sensitive surface plasman resonance biosensor (PS-SPRB) which is able to convert the phase modulation into amplitude modulation analytically via a differential amplifier. PS-SPRB is able to measure biomolecule interactions at ultra-low concentration relying on the properties of phase sensitive detection at shot-noise detection in a real-time. The common-phase noise-rejection mode is provided in PS-SPRB to be able to immune the background phase noise efficiently. The experimental results confirm the detection sensitivity of 0.00001 wt % concentration of sucrose solution and 10 fg/ml mouse IgG interaction with anti IgG in real time.

原文英語
主出版物標題Optical Diagnostics and Sensing IX
DOIs
出版狀態已出版 - 2009
事件Optical Diagnostics and Sensing IX - San Jose, CA, 美國
持續時間: 26 01 200927 01 2009

出版系列

名字Progress in Biomedical Optics and Imaging - Proceedings of SPIE
7186
ISSN(列印)1605-7422

Conference

ConferenceOptical Diagnostics and Sensing IX
國家/地區美國
城市San Jose, CA
期間26/01/0927/01/09

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