Using high-performance liquid chromatography with UV detector to quantify exhaled leukotriene B4 level in nonatopic adults

Gwo Hwa Wan, Dah Chin Yan, Hui Yun Tseng, Jian Tao Lee, Yu Wen Lin*

*此作品的通信作者

研究成果: 期刊稿件文章同行評審

1 引文 斯高帕斯(Scopus)

摘要

This study aimed to evaluate the feasibility of the chemical method to analyze exhaled breath condensate (EBC) leukotriene B4 (LTB4) level in humans. High-performance liquid chromatography with a UV detector was applied to quantify the inflammatory biomarker. The LTB4 concentration in the concentrated pooled EBC samples was 1.19ng/μL, and the average LTB4 concentration of each EBC sample was 15.38ng/μL. This analytical technique was feasible to evaluate the levels of inflammatory mediators such as LTB4 in human EBCs without any complicated sample pretreatment processes.

原文英語
頁(從 - 到)566-568
頁數3
期刊Journal of the Formosan Medical Association
113
發行號8
DOIs
出版狀態已出版 - 08 2014

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