vHDvDB 2.0: Database and Group Comparison Server for Hepatitis Delta Virus

Chi Ching Lee*, Yiu Chung Lau, You Kai Liang, Yun Hsuan Hsian, Chun Hsiang Lin, Hsin Ying Wu, Deborah Jing Yi Tan, Yuan Ming Yeh, Mei Chao*

*此作品的通信作者

研究成果: 期刊稿件文章同行評審

摘要

The hepatitis delta virus (HDV) is a unique pathogen with significant global health implications, affecting individuals who are coinfected with the hepatitis B virus (HBV). HDV infection has profound clinical consequences, manifesting either as coinfection with HBV, resulting in acute hepatitis and potential liver failure, or as superinfection in chronic HBV cases, substantially increasing the risk of cirrhosis and hepatocellular carcinoma. Given the complex dynamics of HDV infection and the urgent need for advanced research tools, this article introduces vHDvDB 2.0, a comprehensive HDV full-length sequence database. This innovative platform integrates data preprocessing, secondary structure prediction, and epidemiological research tools. The primary goal of vHDvDB 2.0 is to consolidate HDV sequence data into a user-friendly repository, thereby facilitating access for researchers and enhancing the broader scientific understanding of HDV. The significance of this database lies in its potential to streamline HDV research by providing a centralized resource for analyzing viral sequences and exploring genotype-specific characteristics. It will also enable more in-depth research within the HDV sequence domains.

原文英語
文章編號1254
期刊Viruses
16
發行號8
DOIs
出版狀態已出版 - 05 08 2024

文獻附註

Publisher Copyright:
© 2024 by the authors.

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